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Wellbutrin SR (Bupropion) is a pharmaceutical prescription antidepressant and antismoking drug.

As a smoking cessation aid under the brand name Wellbutrin, it appears to work by reducing nicotine cravings and the symptoms of nicotine withdrawal. It also helps to prevent the unwanted weight gain which often accompanies stopping smoking. One thing to remember when taking Wellbutrin is that it is important to take it earlier in the day to help prevent insomnia at night and if two doses are taken one must be taken eight hours after the first so the first one should be taken on waking.